Tips: 10 AI Prompts for Clinical Researchers

Designing More Effective Text Messaging for Research Studies

Disclaimer: These prompts are provided as a starting point to help you think through your study's text messaging design. AI-generated content can contain errors or omissions. Always review any output with your IRB, legal, and compliance teams before using it in your research or submitting it for approval. Mosio is not responsible for how AI-generated content is applied to your study.

The following prompts are designed to help clinical researchers use AI tools like Claude (or ChatGPT) to plan, write, and refine text messaging communications for their studies. Each prompt is copy-paste ready: simply fill in the bracketed placeholders with your study details.

1. Message Cadence Design

"I'm running a [12-week behavioral intervention] study with [60 adult participants]. Help me design a text messaging schedule that maximizes engagement without causing fatigue. Include suggested frequency, timing, and how to vary message types across the study timeline."
 

2. Plain Language Audit

"Review these text messages for my clinical study and rewrite any that are above a 6th-grade reading level. Flag medical jargon and suggest plain-language replacements. [Paste messages]"
 

3. Consent Language for SMS

"Draft clear, IRB-friendly opt-in language for a study that will send participants text messages about appointment reminders and weekly check-ins. It should be brief enough to work as a first SMS."
 

4. Reminder Message Variations

"Write 5 variations of a study check-in reminder text for an intervention study. Vary the tone from neutral to motivational. Each must be under 160 characters and avoid sounding clinical or robotic."

Note: Mosio enables you to send messages longer than 160 characters — but keeping messages within this limit helps researchers make the most of their message and segment credits.
 

5. Non-Response Protocol

"A participant in my study hasn't responded to their last 3 check-in texts. Draft a sequence of 2 follow-up messages — one warm nudge and one escalation — that stay within IRB-safe boundaries and don't feel punitive."
 

6. Cultural Adaptation Review

"My study is recruiting participants from a specific cultural community. Review these texts and flag any phrases that may not translate well culturally — not just linguistically. Then suggest culturally adapted alternatives."
 

7. Branching Logic Design

"I want to send a weekly well-being check-in text with a 1–5 scale response. Help me design a branching message logic tree: what should participants receive based on each response? Flag which branches might need clinical review."
 

8. Burden Assessment

"Here is my full text messaging plan for a [16-week] study. Analyze it from a participant burden perspective — identify any weeks where volume or emotional weight may be too high, and suggest adjustments."
 

9. Dropout Risk Messaging

"What are evidence-informed strategies for reducing early dropout in SMS-based research studies? Suggest 3 message types I should include in weeks 1–2 to build habit and trust with new participants."
 

10. Study Wrap-Up and Offboarding

"Draft a 3-message end-of-study sequence for a [6-month] longitudinal study. The messages should thank participants, explain next steps, and transition them off regular texts without leaving them feeling abruptly cut off."